The Mortal Instruments: City of Bones is a 2013 German-Canadian action-adventure fantasy film based on the first book of The Mortal Instruments series by Cassandra Clare. The story takes place in an urban and contemporary New York City. Directed by Harald Zwart, the film stars an international cast, including Lily Collins, Jamie Campbell Bower, Robert Sheehan, Kevin Zegers, Jemima West, Godfrey Gao, Lena Headey, Jonathan Rhys Meyers, Aidan Turner, Kevin Durand, and Jared Harris. It was released in theaters on August 21, 2013.

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New York City teenager Clary Fray (Lily Collins) begins seeing a strange symbol, worrying her mother Jocelyn Fray (Lena Headey) and her mother's friend Luke Garroway (Aidan Turner). Later, at a nightclub with her friend, Simon Lewis (Robert Sheehan), Clary is the only person who sees Jace Wayland (Jamie Campbell Bower) killing a man. Meanwhile, Jocelyn is abducted by two men, Emil Pangborn (Kevin Durand) and Samuel Blackwell (Robert Maillet), but she is able to call Clary and warn her about someone named Valentine. Jocelyn drinks a potion putting her in a comatose state. Returning home, Clary finds her mother missing and is attacked by a demon. Jace, a Shadowhunter, appears and kills it. Jocelyn was also Shadowhunter (also called Nephilim), a warrior that slays demons, and Clary has inherited her powers, including the ability to use runes.

Madame Dorothea (C. C. H. Pounder), the Fray's neighbor and a witch, deduces that Pangborn and Blackwell seek the Mortal Cup, one of the three Mortal Instruments given to the first Shadowhunter by the Angel Raziel. It allows normal humans to become half-Angel Shadowhunters. Simon, now able to see Jace, arrives and they go to Luke's bookstore. Pangborn and Blackwell are interrogating Luke there, who claims he cares nothing for Jocelyn and only wants the Mortal Cup. The trio escapes to the Shadowhunters' hideout, the Institute, where Clary and Simon meet Shadowhunters Alec Lightwood (Kevin Zegers) and Isabelle Lightwood (Jemima West), and their leader, Hodge Starkweather (Jared Harris). He reveals that Valentine Morgenstern (Jonathan Rhys Meyers), an ex-Shadowhunter who betrayed the Nephilim seeks the Mortal Cup to control all Shadowhunters and demons.